Uroplakin III is not a major candidate gene for primary vesicoureteral reflux
نویسندگان
چکیده
منابع مشابه
Ablation of Uroplakin III Gene Results in Small Urothelial Plaques, Urothelial Leakage, and Vesicoureteral Reflux
Urothelium synthesizes a group of integral membrane proteins called uroplakins, which form two-dimensional crystals (urothelial plaques) covering >90% of the apical urothelial surface. We show that the ablation of the mouse uroplakin III (UPIII) gene leads to overexpression, defective glycosylation, and abnormal targeting of uroplakin Ib, the presumed partner of UPIII. The UPIII-depleted urothe...
متن کاملPrimary Vesicoureteral Reflux in Children in Southern Iran
Background: Experience with vesicoureteral reflux (VUR) differs in different centers and there is plenty of controversies.Objective: To evaluate the outcome of primary VUR complications and the rate of recurrence of UTI.Methods: In a retrospective study, the medical charts of all infants and children with primary VUR who were followed up by one nephrologist were reviewed. During 16 years, 271...
متن کاملMild Postnatal Hydronephrosis Is Not Associated With Increased Vesicoureteral Reflux
Background: Antenatal hydronephrosis is known to be associated with vesicoureteral reflux (VUR). However, the incidence of VUR in postnatally diagnosed hydronephrosis is unknown. Hypothesis: The prevalence of VUR is increased in infants diagnosed with hydronephrosis on postnatal ultrasonography. Methods: Infants admitted to our NICU between January 1998 and September 2007 and diagnosed with hyd...
متن کاملPrimary vesicoureteral reflux in Iranian children.
BACKGROUND Experience with vesicoureteral reflux (VUR) differs in different centers and there are plenty of controversies. OBJECTIVE The aim of this study was to evaluate the outcome of primary VUR complications and the rate of recurrence of UTI. METHODS The medical charts of all infants and children with primary VUR who were followed up by two nephrologist were reviewed. During 19 years (1...
متن کامل[Management of primary vesicoureteral reflux in children].
The management of primary vesicoureteral reflux (VUR) in child suffered major changes by focusing on the medical treatment in order to prevent the urinary tract infections and the occurrence of postinfectious renal scars. Continuous antibiotic prophylaxis and the follow-up by serial cystography of the spontaneous resolution of the reflux are considered nowadays the best choice in most of the ca...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2004
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5201322